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Uveal Melanoma: Better Survival With Liver Directed Therapy.

      For patients with uveal melanoma, the most common eye cancer in adults, survival outcomes have improved in recent years, after treatment modalities shifted from systemic to liver-directed therapies. The finding comes from researchers at the Thomas Jefferson University in Philadelphia, Pennsylvania, and was presented at the recent American Society of Clinical Oncology (ASCO) 2018… Read More »Uveal Melanoma: Better Survival With Liver Directed Therapy.

    FDA Approves Pegfilgrastim Biosimilar for Cancer Infection Risk

      Author: Nick Mulcahy The U.S. Food and Drug Administration has approved the first biosimilar to pegfilgrastim (Neulasta, Amgen), a granulocyte colony-stimulating factor used to reduce infection risk in patients with cancer. The new product is pegfilgrastim-jmdb ( Fulphila , Mylan GmbH), approved for use to decrease the risk for infection in patients with nonmyeloid cancer who are receiving… Read More »FDA Approves Pegfilgrastim Biosimilar for Cancer Infection Risk

      ‘Oncology Done Right Is About Balance’: Weighing Immunotherapy Side Effects

        Author: Mark G. Kris, MD Hello. This is Mark Kris from Memorial Sloan Kettering. I am speaking to you today about three papers that appeared in JAMA Oncology on January 11, 2018, dealing with the adverse effects of immune checkpoint inhibitors. There was a commentary and two papers. My issue with these presentations is the lack of discussion of benefits… Read More »‘Oncology Done Right Is About Balance’: Weighing Immunotherapy Side Effects

        Risk of Methotrexate Dosing Errors Prompts EMA Review

          Reporter: Megan Brook The European Medicines Agency (EMA) is reviewing the risk of dosing errors with medicines containing methotrexate. The review is based on “continued reports of overdose,” the agency announced today. Methotrexate is used to treat various inflammatory conditions, such as arthritis, psoriasis, and some cancers, such as acute lymphoblastic leukemia. Methotrexate can be taken… Read More »Risk of Methotrexate Dosing Errors Prompts EMA Review

          Rucaparib for Ovarian Cancer OK’d for Approval in Europe

            Reporter: Zosia Chustecka A new option for the treatment of ovarian cancer could soon be available in Europe: the PARP (poly [adenosine diphosphate-ribose] polymerase) inhibitor rucaparib (Rubraca, Clovis). At its latest meeting the Committee for Medicinal Products for Human Use (CHMP), the scientific committee of the European Medicines Agency (EMA) recommended a conditional marketing authorization for rucaparib… Read More »Rucaparib for Ovarian Cancer OK’d for Approval in Europe

            Clinicians as Communication Coaches – Preparing Patients for Difficult Conversations

              Author: Betty R. Ferrell, PhD, RN Tired of Treatment Paulo is a 49-year-old man with a recurrent brain tumor; he is now hospitalized after experiencing seizures. The tumor was diagnosed when Paulo was 44 years of age, and he has had extensive surgery, chemotherapy, and radiation therapy. Three months ago, the brain tumor team advised Paulo… Read More »Clinicians as Communication Coaches – Preparing Patients for Difficult Conversations

              How smoking ruins your lungs

                Smoking is one of the main causes of preventable deaths throughout the world. When smoke enters the human body it affects nearly each and every organ leading to many life-threatening diseases. The poisons from the cigarette, which are basically tar and other chemicals when entering the bloodstream, are responsible for narrowing the arteries as well as… Read More »How smoking ruins your lungs